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HomeMental HealthFacet Results of Trazodone to Be Conscious of — Talkspace

Facet Results of Trazodone to Be Conscious of — Talkspace

Printed on: 23 Might 2023

Side Effects of Trazodone to Be Aware of

Trazodone is an antidepressant medicine that’s sometimes prescribed to deal with depressive dysfunction and anxiousness dysfunction and is used off-label for insomnia sleep problem. Trazodone works by altering serotonin ranges within the mind to enhance temper and sleep high quality. Whereas Tradozone use may be useful, there are widespread negative effects and dangers to grasp and think about like with each medicine.

Realizing the negative effects of Trazodone drugs is essential should you’re contemplating taking this drug to alter your serotonin ranges — maintain studying to study extra. We’re overlaying every widespread aspect impact, extreme however uncommon results to concentrate on, and how you can handle any adversarial results you may expertise after you begin taking this drug.   

Frequent Facet Results of Trazodone

Probably the most outstanding Trazodone aspect impact is drowsiness. In actual fact, the drug is commonly used off-label to deal with insomnia. Different widespread negative effects of Trazodone can embody:

  • Nausea
  • Vomiting
  • Dry mouth 
  • Throat irritation
  • Headache
  • Stomach ache
  • Constipation
  • Low blood strain
  • Itchy eyes
  • Disorientation
  • Blurred imaginative and prescient
  • Coordination points
  • Fainting

Much less Frequent Facet Results of Trazodone

Weight achieve 

Does Trazodone trigger weight achieve? Gaining weight is never skilled when taking Trazodone drugs. Scientific trials advised that simply 1% of individuals may achieve weight after taking it. Nevertheless, some later analysis exhibits each weight achieve and loss are doable. 


Incontinence is one other uncommon aspect impact of excessive doses of Trazodone. Analysis suggests that individuals with urinary incontinence ought to severely think about this and maybe seek the advice of with a healthcare supplier earlier than taking Trazodone. 

Sexual dysfunction

In accordance with research, an estimated 1.5% of individuals taking Trazodone could have decreased intercourse want as a result of drug. Most individuals see a return of sexual want and genital sensitivity in time, although. 

Psychiatry and Prescriptions On-line

Obtain an analysis and prescription for psychological well being medicine (if wanted) from a psychiatry-trained medical supplier.

Critical Facet Results of Trazodone

Critical negative effects from taking Trazodone embody suicidal ideas, worsening signs of despair, and decreased immune system effectivity. 

“There are a few negative effects of Trazodone that we have to watch. The primary one is an irregular coronary heart rhythm, too quick or too gradual. It could additionally lower the immune system’s effectivity, resulting in extra colds and infections. Bowel motion and urination irregularities will also be trigger for concern. Unexplained bruising, complications, aches and pains, confusion, nervousness, fainting, coordination points, and blurred imaginative and prescient that choose up in frequency needs to be monitored.”

Talkspace therapist Meaghan Rice, PsyD, LPC

Different reactions can happen on account of Trazodone use, together with: 

  • Seizures 
  • Probability in coronary heart fee (quickening or slowing irregular heartbeat)
  • Adjustments in conduct, equivalent to aggression or agitation
  • Hallucinations
  • Issue respiratory

Should you see any of those indicators affecting psychological well being equivalent to suicidal ideas whereas on Trazodone, contact your physician instantly.  

Do Trazodone Facet Results Go Away?

The excellent news is that the majority of Trazodone’s negative effects will resolve as your physique adjusts to having the drug in your system. Nevertheless, if any widespread aspect impact persists or worsens, you must ask your physician or healthcare supplier about altering your dosage or switching drugs altogether.

How lengthy do Trazodone negative effects final?

Whereas most individuals discover adversarial negative effects start to subside in time, some could expertise them for prolonged durations and need to discuss to their physician. 

Learn how to Handle Trazodone Facet Results

Should you’re experiencing any disagreeable negative effects associated to Trazodone, your physician may give you concepts on how one can handle every adversarial aspect impact. 

For instance, easy methods to fight Trazodone negative effects embody:

  • Monitoring your signs
  • Adjusting dosage quantity
  • Altering the time of day you are taking it, or whether or not you are taking it with meals or with out 
  • Making way of life modifications equivalent to yoga, meditation, and exercising usually  
  • Hydrating
  • Utilizing pure treatments like consuming ginger tea for nausea or taking probiotics for intestine well being

“Managing Trazodone negative effects might embody consuming further water, supporting a wholesome way of life, eliminating drug use — particularly NSAIDS and cigarette smoking — limiting or eliminating caffeine and/or alcohol, telling your physician something and the whole lot you’re already taking, being cautious about dangerous actions that don’t enable room for the sedative impact of Trazodone, and ensuring your physician is aware of the whole lot about earlier medical circumstances.”

Talkspace therapist Meaghan Rice, PsyD, LPC

See If Trazodone Is Proper for You with Talkspace Psychiatry

Trazodone negative effects can vary from delicate to extreme, and it’s essential for anybody contemplating this medicine to concentrate on them. Although most negative effects are short-term, figuring out that they could nonetheless happen is crucial. That is particularly essential should you’re contemplating stopping medicine as there’s a probability of experiencing Trazodone withdrawal signs. 

Should you’re trying into whether or not Trazodone could also be a superb match to your psychological well being wants, Talkspace on-line psychiatry companies supply personalised assessments with licensed professionals who can assist decide if this or every other medicine may gain advantage you. Get assist  at present.


  1. DailyMed – Trazodone Hydrochloride Pill. U.S. Nationwide Library of Medication. Accessed March 10, 2023. 
  2. Gica S. Investigation of the impact of Trazodone on spontaneous and acetylcholine-induced bladder detrusor easy muscle contractions. Dusunen Adam:The Journal of Psychiatry and Neurological Sciences. 2022. doi:10.14744/dajpns.2022.00170.  Accessed March 10, 2023. 
  3. Trazodone hydrochloride – Drug Abstract. Trazodone Hydrochloride (trazodone hydrochloride) dose, indications, adversarial results, interactions… from PDR.internet. https://www.pdr.internet/drug-summary/Trazodone-Hydrochloride-trazodone-hydrochloride-3033.1692. Accessed March 10, 2023. 

Talkspace articles are written by skilled psychological health-wellness contributors; they’re grounded in scientific analysis and evidence-based practices. Articles are extensively reviewed by our crew of medical consultants (therapists and psychiatrists of varied specialties) to make sure content material is correct and on par with present business requirements.

Our purpose at Talkspace is to supply probably the most up-to-date, precious, and goal info on psychological health-related subjects with a purpose to assist readers make knowledgeable selections.

Articles include trusted third-party sources which can be both instantly linked to within the textual content or listed on the backside to take readers on to the supply.

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